Medicines are sometimes prescribed according to the weight of the patient in kilograms. This requires an additional calculation to figure out the dose of the patientu2019s weight before the administration dose can be calculated. For example, a prescription drug is 10mg/kg. To calculate the prescription, you must have an accurate weight for the person in kilograms and then multiply this by the dosage specified. For example, if the weight of the person was 12kg, then the dose would be 10mg/kg x 12kg = 120 mg.